Product Description
Product Name :Gatifloxacin
Synonyms :1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Molecular Formula: C19H22FN3O4
Molecular Weight: 375.3941
InChI: InChI=1/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
CAS Registry Number: 112811-59-3
Density :1.386g/cm3
Boiling point :607.8°C at 760 mmHg
Refractive index: 1.616
Flash point :321.4°C
Certification of Analysis
ITEM
|
SPECIFICATION
|
RESULT
|
Description
|
White or light yellow crystalline powder
|
Conform
|
Water %
|
4.0-8.0
|
6.2
|
Related Substance %
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≤1.0
|
0.45
|
Residue of Ignition %
|
≤0.2
|
0.13
|
Heavy Metals %
|
≤0.002
|
Conforms
|
Assay %
|
≥98.50
|
99.32
|
Fluorine %
|
≥4.6
|
4.8
|
Clarity (650nm) T
|
≥95.0
|
98.8
|
Color Index (420nm) A
|
≤0.25
|
0.15
|
Function&Application
Function
This product is mainly used by a variety of infections caused by sensitive pathogens of diseases, including acute exacerbation of chronic bronchitis, acute sinusitis, community acquired pneumonia, simple urinary tract infection (cystitis) and complicated urinary tract infection, acute pyelonephritis, the male urinary tract inflammation or rectal gonococcal infection and gonococcal cervical infection in women
Application
Gatifloxacin is a fluoroquinolone antibiotic, with potent activity against Gram-negative and Gram-positive bacteria. Gatifloxacin also inhibits bacterial topoismerase II (Topo II)