Factory supply Pheniramine maleate CAS 132-20-7
Application:
Pharmaceutical raw material
Product Name
|
Pheniramine maleate
|
Melting point
|
104-108°C
|
Brand
|
Lihe
|
Boiling point
|
489.25°C (rough estimate)
|
Cas number
|
132-20-7
|
Density
|
1.2233 (rough estimate)
|
EINECS
|
205-051-4
|
Refractive index
|
1.6800 (estimate)
|
Molecular weight
|
356.42
|
Flash point
|
N/M
|
Purity |
99% min |
Usage |
Pheniramine, a H1-receptor antagonist, is an antihistamine with anticholinergic and sedative properties. Pheniramine is used to treat allergic conditions such as hay fever or urticaria. |
Appearance |
White Powder |
Pheniramine is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.
Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself. As an example, Neo Citran contains pheniramine.
Derivatives of pheniramine include chlorphenamine, dexchlorpheniramine, dexbrompheniramine, dexchlorpheniramine, triprolidine, and brompheniramine. Two other halogenated derivatives, iodopheniramine and fluorpheniramine, are currently in use for research on combination therapies for malaria and some cancers. The halogenation of pheniramine increases its potency by 20-fold.
Pheniramine may cause drowsiness or bradycardia, and over-dosage may lead to sleep disorders. Overdose may lead to seizures, especially in combination with alcohol. People combining with cortisol in the long term should avoid pheniramine as it may cause lowered levels of adrenaline (epinephrine) which may lead to loss of consciousness.
Item
|
Requirements
|
Test Results
|
Appearance
|
White crystalline powder
|
Complies
|
Solubility
|
Soluble in water,practically insoluble in methylene chloride, sparingly soluble in dilute mineral acids and dissolves in dilute alkaline solutions
|
Complies
|
Identification
|
|
Infrared absorption
|
The infrared absorption spectrum of the sample should correspond to that of pamidronate disodium pentahydrate CRS
|
Complies
|
Chemical reaction
|
It should give reaction of sodium
|
Complies
|
Appearance of solution
|
The solution is clear and not more intensely coloured than reference solution Y6
|
|
pH
|
7.8~8.8
|
8.0
|
Impurity A
|
≤0.50%
|
Not detected
|
Impurity B
|
≤0.50%
|
Not detected
|
Impurity C
|
≤0.50%
|
Not detected
|
Water(KF)
|
23.0%~27.0%
|
24.4%
|
Heavy metals
|
≤20ppm
|
<20ppm
|
Assay (dried basis)
|
98.0~101.0%
|
99.1%
|
Lihe Service Details:
MOQ
|
100g
|
Supply Ability
|
Bulk quatity in stock
|
Sample
|
Available
|
Shelf Life
|
2 Years
|
Packaging
|
If customer no special request, normally aluminum foil bag/drum
|
Delivery
|
Door to Door,safety gurantee
4 big express: DHL, TNT, FedEx, UPS
Post: HKEMS, , etc.
Bulk qty for special line, guarantee safety
|
Origin
|
China, Anhui
|
Port
|
Shanghai, Qingdao, Ningbo
|
Payment Terms
|
T/T, L/C, D/P, Western Union, Money Gram, Bitcoin and etc
|
Storage
|
Cool and Dry Place, and Keep From Strong Light
|
English name
|
CAS
|
English name
|
CAS
|
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