375325-64-6
SPhos PdG2
Synonym: 2nd Generation SPhos Precatalyst, Chloro(2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II),
SPhos-Pd-G2
CAS Number: 1375325-64-6
Formula: C38H45ClNO2PPd
Formula Weight: 720.62 g/mol
Appearance (Color) White to Light Yellow to Light Brown
mp 218 °C (dec.)
Caution : air sensitive
shelf life :12 month
Supplier: LPBchem-Benjamin
ISO9001 Manufacturer
Standard laboratory
ligands catalysts synthesis compounds
Related Categories
Buchwald 2nd Generation Palladacycles, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling,
Homogeneous Pd Catalysts, Palladium Catalysts
General description
SPhos Pd G2 is a second generation (G2) precatalyst in which phenethylamine based backbone of the (G1) complex is substituted with a biphenyl-based ligand. This improvement on the previous generation allows creating the active palladium species at room temperature with weak phosphate or carbonate bases. The catalyst proves remarkably adept at achieving a variety of Suzuki-Miyaura couplings among other cross-coupling reactions.
Application
Application in Suzuki-Miyaura coupling:
-Self-arylation of 1-alkyl-3-bromo-2-phenyl-2,1-borazaronaphthalenes to form 2,1-borazaronaphthols.
-- Suzuki–Miyaura coupling of [Ru(bpy)2]+ with 4-carboxyphenylboronic acid.
-Suzuki–Miyaura coupling of β-borylated porphyrins with 2-iodoaniline.