Hydroxybenzotriazole (HOBt), white crystal, 1n-hydroxyl substituted derivative of benzotriazole. It is commonly used as a racemization inhibitor in peptide synthesis. Due to the high activity of DCC, the chiral center of the substrate can not be well preserved in the product. Generally, additives such as hydroxyl benzotriazole are added to reduce the activity of activated esters, thereby inhibiting racemization. See Peptide Synthesis for details. Hydroxybenzotriazole is usually sold as monohydrate crystals (~11.7% water by weight). Anhydrous hydroxyl benzotriazole is explosive, should be careful when using.
Name | 1-Hydroxybenzotriazole hydrate | EINECS | 219-989-7 |
CAS No. | 123333-53-9 | Density | 1.065 g/cm |
PSA | 50.94000 | LogP | 0.66860 |
Solubility | slightly soluble | Melting Point | 155-158°C(lit.)
|
Formula | C6H5N3O.xH2O | Boiling Point | 344.6oC at 760mmHg |
Molecular Weight | 288.266 | Flash Point | 162.2oC |
Transport Information | N/A | Appearance | White to off-white powder |
Density: 1.065g /cm
Boiling point: 344.6ºC at 760mmHg
Melting point: 155-158 °C(lit.)
Flash point: 162.2ºC
Water solubility: slightly soluble
Storage: Store at RT.
Vapor pressure: 3.28E-05mmHg at 25°C
Usage:Used as pharmaceutical intermediate, metal surface treatment agent
COMPANY PROFILE
Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.