(S)-2-Hydroxysuccinic acid is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.
Related Catalog
Natural Products >> Acids and Aldehydes
Research Areas >> Metabolic Disease
Target
Human Endogenous Metabolite
In Vitro
It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[1].
References
[1]. Landete JM, et al. Requirement of the Lactobacillus casei MaeKR two-component system for L-malic acid utilization via a malic enzyme pathway. Appl Environ Microbiol. 2010 Jan;76(1):84-95.
Literature: Journal of the American Chemical Society, , vol. 114, # 27 p. 10704 - 10710
L-Aspartic acid
56-84-8
~%
L-(-)-Malic aci...
97-67-6
Literature: Journal of the American Chemical Society, , vol. 58, p. 1675,1677 Journal of the American Chemical Society, , vol. 60, p. 1800 Journal of the American Chemical Society, , vol. 73, p. 1827
Precursor & DownStream
Precursor 9
Previous 1/3 Next
CAS#:1009815-87-5 Largazole
CAS#:328-42-7 Oxaloacetic acid
CAS#:56-84-8 L-Aspartic acid
CAS#:110-17-8 fumaric acid
DownStream 10
Previous 1/3 Next
CAS#:101469-91-4 N-Benzyl-(3S)-h...
CAS#:341031-54-7 Sunitinib malate
CAS#:328-42-7 Oxaloacetic acid
CAS#:75-07-0 ch3cho
Customs
HS Code
2918199090
Summary
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles11
More Articles
Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)
Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...
Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.
Clin. Chem. 40(6) , 862-6, (1994)
Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 457(7231) , 910-4, (2009)
Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...
Synonyms
hydroxy-butanedioic acid
(S)-2-hydroxysuccinic acid
Butanedioic acid, 2-hydroxy-
Hydroxybutandisaeure
MALIC ACID, (DL)
EINECS 202-601-5
2-hydroxybutane-1,4-dioic acid
Malic acid
Malic acid, dl-
DL-MALIC ACID
MFCD00064213
2-Hydroxy-succinic acid
DL-Hydroxybutanedioic acid
L(-)-Malic Acid
R,S(±)-Malic acid
Butanedioic acid, hydroxy-
alpha-Hydroxysuccinic acid
(±)-1-Hydroxy-1,2-ethanedicarboxylic Acid
UNII:817L1N4CKP
alpha-hydroxysuccinicacid
hydroxysuccinic acid
DL(+/-)-MALIC ACID
R,S-Malic acid
2-hydroxybutanedioic acid
2-Hydroxysuccinic Acid
a-Hydroxysuccinic Acid
(±)-Malic Acid
L-Malic acid
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.
China
CAS#:110-17-8
CAS#:101469-91-4
CAS#:341031-54-7
CAS#:75-07-0
