9-Phenanthrol (9-Hydroxyphenanthrene) is a potent and selective human TRPM4 inhibitor, with an IC50 of 20 μM. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].
[1]. Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8(7):e70587.
Chemical & Physical Properties
Density
1.2±0.1 g/cm3
Boiling Point
404.5±14.0 °C at 760 mmHg
Melting Point
139-143ºC
Molecular Formula
C14H10O
Molecular Weight
194.23
Flash Point
197.7±12.0 °C
Exact Mass
194.073166
PSA
20.23000
LogP
3.94
Vapour Pressure
0.0±1.0 mmHg at 25°C
Index of Refraction
1.754
Storage condition
Refrigerator
MSDS
9-Phenanthrol MSDS(Chinese)
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
SF8288000
CHEMICAL NAME :
9-Phenanthrol
CAS REGISTRY NUMBER :
484-17-3
BEILSTEIN REFERENCE NO. :
2047057
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H10-O
MOLECULAR WEIGHT :
194.24
WISWESSER LINE NOTATION :
L B666J HQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
5 mg/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 20,1297,1971
Literature: Fu, Jian-Min; Snieckus, Victor Canadian Journal of Chemistry, 2000 , vol. 78, # 6 p. 905 - 919
Customs
HS Code
2906299090
Summary
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles29
More Articles
Detection of polycyclic aromatic hydrocarbons (PAHs) in raw menhaden fish oil using fluorescence spectroscopy: Method development.
Environ. Toxicol. Chem. 34 , 1946-58, (2015)
Raw menhaden fish oil was developed for biomonitoring polycyclic aromatic hydrocarbons (PAHs) using fluorescence spectroscopy. Menhaden (Genus Brevoortia) were collected in 2010 and/or 2011 from Delaw...
Shear stress induces a longitudinal Ca(2+) wave via autocrine activation of P2Y1 purinergic signalling in rat atrial myocytes.
J. Physiol. 593 , 5091-109, (2015)
Atrial myocytes are exposed to shear stress during the cardiac cycle and haemodynamic disturbance. In response, they generate a longitudinally propagating global Ca(2+) wave. Here, we investigated the...
Application of nano-sized multi-template imprinted polymer for simultaneous extraction of polycyclic aromatic hydrocarbon metabolites in urine samples followed by ultra-high performance liquid chromatographic analysis.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 985 , 110-8, (2015)
Nano-sized molecularly imprinted polymer (nMIP) was synthesized through precipitation polymerization method and used it as solid phase extraction (SPE) sorbent for the selective and simultaneous extra...
Synonyms
9-Phenanthrol
Phenanthren-9-ol
MFCD00082298
EINECS 207-602-4
9-Phenanthrenol
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.
China
