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Esomeprazole magnesium trihydrate

Basic information Safety Related Supplier
Esomeprazole magnesium trihydrate Basic information
Esomeprazole magnesium trihydrate Chemical Properties
  • Melting point:184-189°C (dec.)
  • storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
  • solubility Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
  • form neat
  • InChIKeyVEVZQDGATGBLIC-UHFFFAOYSA-N
  • CAS DataBase Reference217087-09-7(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22
  • WGK Germany 3
  • HS Code 2933399090
Esomeprazole magnesium trihydrate Usage And Synthesis
  • Chemical PropertiesOff-White Powder
  • UsesS-Form of Omeprazole. Gastric proton-pump inhibitor
  • Usesesomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
    1. Zollinger-Ellison syndrome
    2. Peptic ulcer, site unspecified
    3. Duodenal ulcer
    4. Gastric ulcer
    5. Gastro-oesophageal reflux disease
    Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
    1. Gastro-Oesophageal Reflux Disease (GORD):
    2. treatment of erosive reflux oesophagitis;
    3. long-term management of patients with healed oesophagitis to prevent relapse;
    4. symptomatic treatment of gastro-oesophageal reflux disease (GORD).
    In combination with appropriate antibiotics for:
    1. healing of duodenal ulcer associated with Helicobacter pylori;
    2. eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
    3. Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
    4. Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
    5. Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.
  • brand nameNexium (AstraZeneca).
Esomeprazole magnesium trihydrate(217087-09-7)Related Product Information
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