Diflumetorim is used in pesticide formulations functioning as a fungicide.
ChEBI: 5-chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-amine is a member of the class of aminopyrimidines that is 5-chloro-6-methylpyrimidin-4-amine in which one of the amino hydrogens is replaced by a 1-[4-(difluoromethoxy)phenyl]propyl group. It is an aminopyrimidine, an organochlorine compound, an organofluorine compound, an aromatic ether and a secondary amino compound.
The production of diflumetorim begins with the formation of a pyrimidinamine core, which is selectively chlorinated at the 5-position and methylated at the 6-position. A key step involves nucleophilic substitution to attach a 4-(difluoromethoxy)phenylpropyl side chain to the nitrogen atom, enhancing lipophilicity and systemic activity. The resulting compound, 5-chloro-N-[1-[4-(difluoromethoxy)phenyl]propyl]-6-methylpyrimidin-4-amine, is purified and formulated.
Protectant and curative activity, inhibition of complex I NADH Oxido-reductase.
