C18 Ceramide-1-Phosphate-d3 (d18:1/18:0-d3)

C18 Ceramide-1-phosphate-d₃ is intended for use as an internal standard for the quantification of ceramide-1-phosphate by GC- or LC-MS. Ceramide-1-phosphate is an endogenous bioactive sphingolipid that is formed via ATP-dependent conversion of C18 ceramide by ceramide kinase.¹ It stimulates DNA synthesis and cell division, acts as a secondary messenger, and is involved in multiple cellular processes including phagocytosis, inflammatory responses, and tumorigenesis.

1. Hait, N.C., and Maiti, A. The role of sphingosine-1-phosphate and ceramide-1-phosphate in inflammation and cancer Mediators Inflamm. ,4806541(2017).