Lithium chloroacetylide is a nucleophilic organolithium reagent that reacts with a variety of electrophiles.
Lithium chloroacetylide is prepared in ether solution under anhyd conditions by treatment of cis- or trans-1,2- dichloroethylene with 2 equiv Methyllithium at 0 °C under N2.
Dry lithium chloroacetylide is explosive (as are the other metal haloacetylides), but may be safely handled and kept in the solution in which it is prepared under N2.
