1,3-Dioxane has been employed as solvent in the synthesis of 8- and 9-membered dioxazocines and dioxazonines.
ChEBI: 1,3-dioxane is a dioxane and a cyclic acetal.
1,3-dioxane is prepared by the reaction of formaldehyde and 1,3-propanediol in the presence of Br?nsted or Lewis acid catalysts.
Highly flammable. Can form dangerous peroxides when exposed to air. Water soluble.
1,3-DIOXANE is sensitive to heat. 1,3-DIOXANE can react with oxidizers.
ACUTE/CHRONIC HAZARDS: When heated to decomposition 1,3-DIOXANE emits acrid smoke and fumes.
1,3-DIOXANE is flammable.
Dry the dioxane with sodium and fractionally distil it. [Beilstein 19/1 V 11.]