Tunicamycin A
中文名称:Tunicamycin A
英文名称:Tunicamycin A
CAS号:66054-36-2
分子式:C38H62N4O16
分子量:830.93
EINECS号:
Mol文件:66054-36-2.mol
Tunicamycin A 性质
| 密度 | 1.41±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 9.39±0.10(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
Tunicamycin A 用途与合成方法
Tunicamycin V (Tunicamycin A) 是一种核苷天然产物，可抑制细菌 phospho-N-acetylmuramyl-pentapeptide transferase (MraY)，IC50 为 0.35 μM。Tunicamycin V 具有抗菌活性。
IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))
Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER).
Tunicamycin A 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-N8395 | Tunicamycin A | 66054-36-2 | 1mg | 9300 |
