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NNC 687
Product Name
NNC 687
CAS
128022-68-4
MF
C19H20N2O4
MW
340.37
EINECS
MOL File
128022-68-4.mol
Chemical Properties
Boiling point
477.305±45.00 °C(Press: 760.00 Torr)(predicted)
Density
1.311±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka
6.775±0.40(predicted)
Usage And Synthesis
Uses
ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia[1].
IC 50
D
1
Receptor: 5.8 nM (Ki); D
2
Receptor: > ＞10 000 nM (Ki)
References
[1] Andersen PH, et al. NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists. Eur J Pharmacol. 1992;219(1):45-52. DOI:
10.1016/0014-2999(92)90578-r
NNC 687 Supplier
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +1-00000000000
Email
marketing@targetmol.com
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
TargetMol Chemicals Inc.
Tel
13564774135
Email
marketing@targetmol.com
NNC 687 manufacturers
ADX-10061
Purity:
$2500.00
Inquiry
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NNC 687
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