cepacin A

Cepacin A is an acetylenic antibiotic isolated from fermentation broth of Pseudomonas (Burkholderia) cepacia.

Cepacin A is an acetylenic antibiotic. Cepacin A has antibacterial activity, with a MIC of 0.2 μg/mL against staphylococci. In addition, Cepacin A is somewhat toxic to mice, with an LD50 of 30 mg/kg when administered intraperitoneally[1][2].

[1] Tang C J, et al. Studies Directed to the Total Synthesis of Cepacin A. Preliminary Communication. Helvetica chimica acta, 2004, 87(3): 667-673.
[2] Parker WL, et al. Cepacin A and cepacin B, two new antibiotics produced by Pseudomonas cepacia. J Antibiot (Tokyo). 1984 May;37(5):431-40. DOI:10.7164/antibiotics.37.431