Liarozole (5-20 mg/kg; p.o.; 3 days) reverses the vaginal keratosis caused by estrogen stimulation[5].
Liarozole (40 mg/kg; p.o.; 21 days) reduces tumor burden substantially[6].
| Animal Model: | Ovariectomized rats[5] |
| Dosage: | 5~20 mg/kg |
| Administration: | P.o.; 3 days |
| Result: | Reversed the vaginal keratosis caused by estrogen stimulation. |
| Animal Model: | SCID mice[6] |
| Dosage: | 40 mg/kg |
| Administration: | P.o.; 21 days |
| Result: | Inhibited tumor growth and survival. |
