Enisoprost is the antisecretory prostaglandin derivative. Analogue of Prostaglandin E1 (P838600), which is the primary prostaglandin that is easily crystallized from purified biological extracts.
in vivo
SC 34301 (200 μg/kg; p.o.; once a day for three days) significantly reduces bacterial translocation and improves survival[1].
Animal Model:
BALB/c mice (E. coli, burned)[1]
Dosage:
200 μg/kg
Administration:
P.o.; once a day for three days
Result:
Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
