醋酸普罗瑞林
醋酸普罗瑞林 性质
| 储存条件 | Store at -20°C |
|---|---|
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Water : 50 mg/mL (110.51 mM) |
| 序列 | {pGlu}-His-Pro-NH2 |
醋酸普罗瑞林 用途与合成方法
醋酸普罗瑞林（Protirelin acetate）是Protirelin的醋酸盐形式，可用于改善精神分裂症患者的面部表情、情感融洽和精神运动等症状。Protirelin 是内源性肽促甲状腺激素释放激素 （TRH） 的医药合成类似物，由下丘脑释放的三肽嗜性激素，可刺激垂体前叶释放促甲状腺激素 （TSH） 和催乳素。
Protirelin Acetate 是一种高度保守的神经肽，发挥促甲状腺激素 (TSH) 水平的激素控制作用，及神经调节功能。Thyroid hormone receptor
Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin.
醋酸普罗瑞林 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-P0002A | 醋酸普罗瑞林 | 120876-23-5 | 5 mg | 420 |
| 2026-09-15 | HY-P0002A | 120876-23-5 | 120876-23-5 | 10mg | 700 |
