Basic information Safety Related Supplier

7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN

Basic information Safety Related Supplier
7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN Basic information
7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN Chemical Properties
  • Melting point:115 °C
  • Boiling point:456.1±45.0 °C(Predicted)
  • Density 1.46±0.1 g/cm3(Predicted)
  • storage temp. Keep in dark place,Sealed in dry,2-8°C
  • pka1.95±0.20(Predicted)
7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN Usage And Synthesis
  • UsesJLK 6 is an inhibitor of γ-secretase, selectively inhibits βAPP cleavage.
  • Biological ActivityInhibitor of γ -secretase that selectively inhibits β APP cleavage without affecting other γ -secretase-mediated pathways. Prevents recovery of A β 40 and A β 42 from HEK293 cell overexpressing wild-type or Swedish-mutated β APP (IC 50 ~ 30 μ M) but displays no effect on Notch cleavage and Notch-mediated intracellular signaling. Displays no activity on BACE1, BACE2, α -secretase, the proteosome or GSK3 β .
7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN(62252-26-0)Related Product Information
7-AMINO-4-CHLORO-3-METHOXYISOCOUMARINSupplierMore
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
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  • Company Name:BOC Sciences
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  • Company Name:Shanghai Raise Chemical Technology Co.,Ltd
  • Tel:15026594951 +86-0556-5030631
  • Email:rs@raise-chem.com
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  • Company Name:AdooQ BioScience, LLC
  • Tel:+1 (866) 930-6790
  • Email:info@adooq.com
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  • Company Name:EMMX Biotechnology LLC
  • Tel:888-539-0666
  • Email:info@emmx.com
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