Isocarbamid was produced commercially as a pre-emergence herbicide through imidazolidinone chemistry, involving the condensation of isobutylamine with glyoxal derivatives to form the imidazolidinone ring, followed by carbamoylation to yield the final N-(2-methylpropyl)-2-oxoimidazolidine-1-carboxamide structure. Industrial production required controlled reaction conditions to ensure selectivity and purity, with subsequent purification steps such as recrystallisation to achieve technical-grade material.
