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19-HYDROXY-4-ANDROSTENE-3,17-DIONE

Basic information Safety Related Supplier
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Basic information
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Chemical Properties
  • Melting point:168-169 °C(lit.)
  • Boiling point:485.4±45.0 °C(Predicted)
  • Density 1.19±0.1 g/cm3(Predicted)
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • pka14.90±0.10(Predicted)
  • optical activity[α]/D +190±5°, c = 1 in chloroform
  • BRN 2567249
  • CAS DataBase Reference510-64-5(CAS DataBase Reference)
  • NIST Chemistry Reference19-Hydroxyandrost-4-ene-3,17-dione(510-64-5)
Safety Information
MSDS
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Usage And Synthesis
  • Chemical PropertiesOff-White Solid
  • UsesA novel substituted estrogen as aromatase inhibitor
  • Uses19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.
  • Purification MethodsRecrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.]
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Preparation Products And Raw materials
19-HYDROXY-4-ANDROSTENE-3,17-DIONE(510-64-5)Related Product Information
19-HYDROXY-4-ANDROSTENE-3,17-DIONESupplierMore
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