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Sacubitril Impurity 7 Structure

Sacubitril Impurity 7

Chemical Properties

Boiling point 705.4±60.0 °C(Predicted)
Density  1?+-.0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
form  A crystalline solid
pka 4.59±0.23(Predicted)
color  White to off-white
optical activity [α]/D -35 to -27°, c =1 in methanol

Usage And Synthesis

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