Cyclo(-His-Pro)

Chemical Properties

Melting point	162-164 °C
Boiling point	659.3±48.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
form	A neat oil
pka	12.73±0.40(Predicted)
color	Light yellow to yellow
Cosmetics Ingredients Functions	HUMECTANT ANTIOXIDANT SKIN CONDITIONING - MISCELLANEOUS PRESERVATIVE SKIN PROTECTING
InChI	InChI=1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
InChIKey	NAKUGCPAQTUSBE-IUCAKERBSA-N
SMILES	[C@@]12([H])CCCN1C(=O)[C@H](CC1=CNC=N1)NC2=O

WGK Germany	3
Storage Class	11 - Combustible Solids

Animal Model:	Sixty two/three month-old male C57BL/6 mice (25-30 g)^[2]
Dosage:	1.8 mg/ear
Administration:	Topical application on the right ear; 30 min prior to TPA
Result:	Reduced TPA-induced ear oedema.