HPOB is a histone deacetylase 6 inhibitor used in the enhancement of anti-cancer drugs.
Biological Activity
HPOB is a very potent, selective inhibitor of HDAC6. HPOB inhibits proliferation of normal and transformed cell lines but does not induce cell death. The compound HPOB potentiates the effects of DNA-damaging cytotoxic anti-cancer drugs.