LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.WARNING This product is not for human or veterinary use.
