3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯
3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯
![3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 结构式](https://img.chemicalbook.com/CAS/GIF/634911-80-1.gif)
3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 性质
| 沸点 | 383.5±37.0 °C(Predicted) |
|---|---|
| 密度 | 1.150 |
| 储存条件 | -20°C |
| 溶解度 | DMSO: 5mg/mL |
| 形态 | <31.2°C 固体,>31.2°C 液体 |
| 酸度系数(pKa) | 10.12±0.46(Predicted) |
| 颜色 | 浅黄至黄色 |
| InChI | InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16) |
| InChIKey | MXOOUCRHWJYCAL-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)CC(NC(OC(C)(C)C)=O)C(=O)CF |
3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 用途与合成方法
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Caspase
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Apoptosis is a pathway of cell death orchestrated by a family of proteases called caspases. Boc-D-fmk inhibits TNFα-stimulated reactive oxygen species (ROS) generation. Boc-D-FMK inhibits apoptosis stimulated by TNF-α with an IC 50 of 39 µM. BocD-fmk at 50 µM prevents genistein-induced apoptosis of p815 cells. Confocal microscopy shows that the release of mitochondrial apoptotic factors is inhibited by BocD-fmk.
Boc-D-FMK-fmk effectively attenuates the hepatocyte apoptosis in bile duct-ligated rats and may improve the survival rates after endotoxin challenge. A single injection of Boc-D-FMK results in longterm protection of MNs against root avulsion-induced death for more than 8 weeks and the Boc-D-FMK-treated MNs are able to regenerate their axons into an implanted PN graft and reinnervate the target muscle.
3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-13229R | 3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 | 634911-80-1 | 1 mg | 1440 |
| 2026-09-15 | HY-13229R | 3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯 | 634911-80-1 | 5 mg | 3000 |
