2-Methyl-1-(methylamino)propan-2-ol was prepared as follows: 1-chloro-2-methyl-2-propanol (103L, 1.00 mmol) was dissolved in 40% methylamine methanol solution (0.5 mL) and stirred in a microwave chemical synthesis unit (CEMDiscover) for 15 min at 100C at 100W. After cooling to room temperature, the solvent was removed by distillation under reduced pressure, acetonitrile (3 mL) was added and the precipitated solid was filtered off. After adding aqueous sodium bicarbonate (10 drops) to the filtrate, the solvent was removed by distillation under reduced pressure to give a crude concentrate of 2-methyl-1-(methylamino)propan-2-ol.
