(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

1. Chiral ligand for ruthenium- catalyzed asymmetric hydrogenation of aromatic ketones.
2. Chiral ligand for iridium-catalyzed asymmetric hydrogenation of quinolines.
3. Chiral ligand for copper- catalyzed asymmetric hydrosilylation of ketones.
4. Synthesis of new chiral 2-functionized-1,2,3,4-tetrahydroquinoline derivatives via asymmetric hydrogenation of substituted quinolines.
5. Rhodium-biphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

White solid

(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in asymmetric hydrogenation.It acts as a ligand used in the asymmetic hydrogenation of β-keto esters, 2-arylacrylates, aryl ketones , and other substrates. Other applications include it is used widely as a Catalyst, when combined with Rh, Ru and Ir precursor.