(+/-)-11-HYDROXY-12E,14Z-EICOSADIENOIC ACID

(±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE and 11(R)-HEDE . 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.^1,2

1. Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase Biochemistry 17(9),1772-1779(1978).
2. Rabinovitch, H., Durand, J., Gualde, N., et al. Metabolism of polyunsaturated fatty acids by mouse peritoneal macrophages: The lipoxygenase metabolic pathway Agents Actions 11(6-7),580-583(1981).