1,1,1,2,3,3,3-heptafluoropropane was mixed with bromine at a molar ratio of 1 to 5:1 and subjected to a multi-stage bromination reaction. Chlorine gas was introduced between each stage of the bromination reaction. The resulting reaction product was washed with water, washed with alkali, and distilled to obtain 2-bromoheptafluoropropane.
2-Bromoheptafluoropropane is a key raw material intermediate for the synthesis of Broflanilide, which is a meta-diamide insecticide for the control of common crop pests, including Lepidoptera, Coleoptera, termites, mosquitoes and flies. Current studies show that Broflanilide has reported excellent insecticidal activity against larvae and adults.
