3',4'-Dihydroxy-2-methylpropiophenone

Chemical Properties

Melting point	79-81℃
Boiling point	372.2±27.0 °C(Predicted)
Density	1.191±0.06 g/cm3(Predicted)
RTECS	NQ5605000
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	White solid.
pka	8.77±0.31(Predicted)
color	Off-White to Pale Beige

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Animal Model:	Male Sprague-Dawley rats (180-250 g)^[1]
Dosage:	0-250 mg/kg
Administration:	i.p.; 10 min
Result:	Inhibited COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity was obtained at 90mg/kg and maximum inhibition of 90% was obtained at 250 mg/kg.