Dystrobrevin-β (β-DB) may be significantly involved in assembling and supporting the dystrophin-associated protein complex (DPC)-like complexes in non-muscle tissues. It is known to interact with the neuronal kinesin heavy chain Kif5A and Kif5B in the brain, suggesting th at β-DB might act as a motor protein receptor involved in the transport of dystrophin-glycoprotein complex (DGC) components to specific sites in the cell.