5-ethyl-6-octyl-[1,2,3]triazolo[1,5-a]pyriMidin-7-aMine

Ametoctradin is a fungicide approved for use in many countries for the control of economically damaging fungal diseases on fruit and vegetables. It has a low aqueous solubility and a low volatility. It tends not to be persistent in soils but can be in aquatic bodies under certain conditions. Based on the substances chemical properties there is a low risk of it leaching to groundwater. It generally has a low to moderate toxicity to biodiversity. It is not highly toxic to humans and no chronic health impacts have been identified.

Ametoctradin acts as a pesticide, and is used in fomulations of insecticides and fungicides.

ChEBI: A member of the class of triazolopyrimidines that is [1,2,4]triazolo[1,5-a]pyrimidin-7-amine carrying additional ethyl and octyl substituents at positions 5 and 6 respectively. A fungicide for the control of late blight and downey mildew on po atoes and other crops including vines.

Selective, preventative, mitochondrial respiration inhibitor by interferring with complex III

Ametoctradin (5-ethyl-6-octyl-[1,2,3]triazolo[1,5-a]pyriMidin-7-aMine) was synthesized through four steps from methyl 3-oxopentanoate and 1h-1,2,4-triazol-5-amine,and its structure was confirmed by 1h Nmr[1].

[1] Synthesis of Ametoctradin and Its Bioactivity. Proceedings of the 15th Annual Meeting of the Pesticide Professional Committee of the Chemical Industry and Engineering Society of China.

Fungicide