alpha-D-Galactopyranosylphenyl isothiocyanate

α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate. Neoglycoproteins are used to identify the presence and sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells and to study membrane lectin-mediated endocytosis.

aGalOC6H4NCS

α-D-Galactopyranosylphenyl isothiocyanate can be used to synthesis Galactosylated a-CDE conjugate[1].

[1] Wada K, et al. Improvement of gene delivery mediated by mannosylated dendrimer/alpha-cyclodextrin conjugates. J Control Release. 2005 May 18;104(2):397-413. DOI:10.1016/j.jconrel.2005.02.016