BO-TAP-1 (also known as BO-PRO®-1) is a cyan fluorescent carbocyanine monomeric dye. BO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make BO-TAP-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments.
The dye is used to detect and count cells (megakaryocyte, erythroblasts, sperms, microorganisms, etc.) and bacteria, perform nucleic acid detection, sequencing, and amplification and as a temperature sensor.
