CD 1530 is a retinoic acid receptor γ selective agonist. In combination with bexxarotene, they inhibit murine oral-cavity carcinogensis. It is found to inhibit heterotopic ossification and preserve tendon stem cell characteristics. It is also associated with RAR signalling in asthma.
Potent and selective RAR γ receptor agonist (K i values are 150, 1500 and 2750 nM for RAR γ , RAR β and RAR α receptors respectively). Activates transcriptional activity (AC 50 = 1.8 nM).
