(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL

Volinanserin is a potent and selective antagonist of the serotonin receptor 5-HT_2A (K_i = 0.36-0.85 nM). It weakly binds 5-HT_2C, α₁-adrenergic, and sigma receptors (K_i = 88, 128, and 87 nM) and much less effectively associates with other serotonin, dopamine, adrenergic, muscarinic acetylcholine receptors and monoamine transporters. Volinanserin displays antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo.

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Volinanserin is a serotonin receptor 5-HT2A antagonist; anti-psychotic.

As a serotonin 5-HT2A receptor antagonist, Volinanserin Hydrochloride Salt can be used as potential controls in various biological studies.

M100907 blocks the serotonin 2A (5-HT2A) receptors and imposes antidepressant-like effects. It may be used for treating dopaminergic anomalies.

M100907 is a selective 5-HT2A Antagonist.

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