(RS)-4-[5-(4-FLUOROPHENYL)-2-METHYLSULFANYL-3H-IMIDAZOL-4-YL]PYRIDIN-2-YL]-(1-PHENYLETHYL)AMINE]

Cell permeable: yes', 'Primary Target
p38 MAP kinase', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 0.38 μM for p38α; 0.16 and 0.039 μM in suppressing LPS-induced TNF-α and IL-1β release, respectively, in human PBMC; ED50 = 1.33 mg/kg in suppressing LPS-induced TNF-α release in mouse