ChemicalBook Product Catalog API Drugs Influencing Immune Function Immunomodulators Cemiplimab

Cemiplimab

Chemical Properties

form	Liquid
color	Colorless to light yellow

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Animal Model:	Female human PD-1×LAG-3 knockin mice (8-10 weeks) with MC38.Ova cells^[2]
Dosage:	10 mg/kg
Administration:	Intraperitoneal injection; five injections within 2 weeks
Result:	Partially inhibited the growth of MC38.Ova tumors and prolonged the survival of mice by administering alone. Significantly increased the proportion of CD4⁺ TILs in IFNγ and TNFα by combined immunotherapy with REGN3767.