Vesamicol is a compound used to synthesize radiolabeled derivatives that can be used as sigma receptor ligands for tumor targeting inhibition and have shown certain potential in cellular uptake, biodistribution and inhibition experiments.
Definition
ChEBI: 2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines.
Biological Activity
Inhibitor of acetylcholine transport (K i = 2 nM). Centrally active following systemic administration in vivo .
References
[1] Astatine-211-labeled aza-vesamicol derivatives as sigma receptor ligands for targeted alpha therapy DOI:10.1016/j.nucmedbio.2023.108369
