Tetanus toxin (830-843) is a powerful neurotoxin that reaches by retroaxonal transport and transcytosis the cytoplasm ofspinal inhibitory intemeurons and blocks their ability to release neurotransmitters[1].
References
[1] Diethelm-Okita BM, et al. Epitope repertoire of human CD4+ T cells on tetanus toxin: identification of immunodominant sequence segments. J Infect Dis. 1997 Feb;175(2):382-91. DOI:10.1093/infdis/175.2.382