Rabbit polyclonal anti-AQP7 antibody is used to tag aquaporin-7 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence of aquaporin-7 in tissues and cells such as the testis, dentritic cells (DC) and uteri wherein it is involved in processes such as sperm motility, antigen uptake and decidualization.
Rabbit polyclonal anti-AQP7 antibody reacts with human aquaporin-7.
Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.
