N-乙酰-2-苄基色胺
N-乙酰-2-苄基色胺 性质
| 熔点 | 44-46°C |
|---|---|
| 沸点 | 434.31°C (rough estimate) |
| 密度 | 1.1045 (rough estimate) |
| 折射率 | 1.6140 (estimate) |
| 储存条件 | -20°C |
| 溶解度 | 在DMSO中的溶解度为5 毫克/毫升 |
| 形态 | 白色至类白色结晶固体。 |
| 酸度系数(pKa) | 16.36±0.46(Predicted) |
| 颜色 | 灰白色至黄色 |
| 水溶解性 | Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water. |
| 稳定性 | -20°C储存 |
| CAS 数据库 | 117946-91-5(CAS DataBase Reference) |
N-乙酰-2-苄基色胺 用途与合成方法
Ki :10.2 nM (human MT2), 158 nM (human MT1)
Luzindole (N-0774) (5-10 μg/ml) inhibits antigen-specific proliferation of the MBP-reactive LV-4 T cell line.
Luzindole (N-0774) (30 mg/kg; i.p.; days 0-5) suppresses experimental autoimmune encephalomyelitis.
Luzindole (N-0774) (30 mg/kg i.p.) reduces the time of immobility in a dose-dependent manner, the effect being more pronounced at midnight (60% reduction) than at noon (39% reduction). The effect of luzindole is time-dependent, showing a maximal effect at 60 min. The anti-immobility effect of luzindole (10 mg/kg i.p.) is prevented by the administration of melatonin (30 mg/kg i.p.). Luzindole (30 mg/kg i.p.) did not modify the time of immobility either at noon or midnight in the albino ND/4 mouse, or in the C57BL/6J mouse, which does not produce melatonin.
| Animal Model: | Twenty-three- to 12-week-old(SJL X PL/J ) F1 mice |
| Dosage: | 30 mg/kg |
| Administration: | i.p.; days 0-5 (between 23: 00 and 1: 00 under conditions of minimal lighting) |
| Result: | Effectively prevented experimental autoimmune encephalomyelitis. |
N-乙酰-2-苄基色胺 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-101254 | N-乙酰-2-苄基色胺 | 117946-91-5 | 1mg | 760 |
| 2024-11-08 | HY-101254 | N-乙酰-2-苄基色胺 | 117946-91-5 | 5mg | 1900 |
