Mapatumumab (10 mg/kg; i.p. for three times) controls tumor growth when combined with irradiation[3].
| Animal Model: | Colo205-xenograft–bearing NMRI (nu/nu) nude mice[3] |
| Dosage: | 10 mg/kg |
| Administration: | Intraperitoneal injection; 10 mg/kg; on days 1, 4, and 8 |
| Result: | Showed no significant differences when used alone, but when combined with irradiation (5×3 Gy, d1–5) showed a pronounced tumor regrowth-delay.
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