mp >300℃.Antifibrinolysis
a2-macroglobulin, IC50= 5.0 μg/ml, a2-fibrinolysin, IC50=0.8
ug/ml); antioxidant (DPPH scavenger, IC50-6.2μmol/L, control
Ascorbic acid, IC50=10.3μmol/L）.
Dieckol, is a naturally occurring phlorotannin found in some brown algal species. Dieckol has anti-bacterial, anti-cancer, anti-oxidant, anti-aging, anti-diabetic, neuroprotective actions[1].
Constitution.of the brown algae Ecklonia kurome and Eisenia bicyclis. Inhibitor of oz-Macroglobulin,glycation and α-amylase.Cryst.
ChEBI: Dieckol is a phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities. It has a role as a metabolite, a radical scavenger, an EC 3.2.1.20 (alpha-glucosidase) inhibitor, a hepatoprotective agent and an anticoagulant. It is a phlorotannin, an aromatic ether and an oxacycle. It is functionally related to a phloroglucinol.
Dieckol remarkably inhibited the lipid accumulation in high fat diet induced animal models[1].
[1] Durairaj Karthick Rajan, et al. Dieckol: a brown algal phlorotannin with biological potential. Biomed Pharmacother. 2021 Oct;142:111988. DOI:
10.1016/j.biopha.2021.111988
