Soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice.
neoisoliquiritin inhibits tumor progression by targeting GRP78-β-catenin signaling in human breast cancer cell xenograft mouse model. A cancer chemopreventive agent.
ChEBI: Isoliquiritin is a monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 2' and 4' and a beta-D-glucopyranosyloxy group at position 4 respectively. It has a role as an antineoplastic agent and a plant metabolite. It is a member of chalcones, a member of resorcinols, a beta-D-glucoside and a monosaccharide derivative. It is functionally related to a trans-chalcone.
