tamitinol

Tamitinol, also known as EMD 21 657, is a neurotropic drug that has been found to help symptoms of obsessive rumination in conjunction with maprotiline.

EMD 21657 is a derivative of Piracetam (HY-B0585). EMD 21657 inhibits LOT compound action potential, and enhances the local anesthetic effect of Hexanol (HY-W032022). EMD 21657 exhibits hemolytic effect, and can be used in research about alcoholic encephalopathy syndrome[1].

[1] Richards CD, et al., Degenerate perturbations of protein structure as the mechanism of anaesthetic action. Nature. 1978 Dec 21-28;276(5690):775-9. DOI:10.1038/276775a0
[2] Saletu B, et al., Treatment of the alcoholic organic brain syndrome with EMD 21657. A derivative of a pyritinolmetabolite: double-blind clinical, quantitative EEG and psychometric studies. Int Pharmacopsychiatry. 1978;13(3):177-92. DOI:10.1159/000468338