Chlobenthiazone is a rice fungicide for controlling blast. It has a moderate aqueous solubility and is highly volatile. Little is known about its environmental fate or ecotoxicological properties. It is moderately toxic to mammals if ingested.
The production of chlobenthiazone involves the chemical synthesis of 4-chloro-3-methylbenzothiazol-2(3H)-one, typically starting from precursors like 4-chloro-2-methoxybenzothiazole. The process includes chlorination and methylation steps, often carried out in organic solvents such as chloroform with bases like triethylamine or DBU to facilitate the reaction, achieving high yields of up to 98%.
Systemic, inhibits infection sites, strong inhibitor of aflatoxin synthesis by A. flavus
