Z-LRGG-AMC (trifluoroacetate salt)

Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T.1 Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.WARNING This product is not for human or veterinary use.

[1] ROSS L. STEIN  Francesco M  Zhijian Chen. Kinetic studies of isopeptidase T: modulation of peptidase activity by ubiquitin[J]. Biochemistry Biochemistry, 1995, 34 39: 12616-12623. DOI: 10.1021/bi00039a017