Z-FR-AMC (trifluoroacetate salt)

Z-FR-AMC is a fluorogenic substrate for cathepsin L.1 Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.WARNING This product is not for human or veterinary use.

[1] CARLOS CARMONA. Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juveniles[J]. Molecular and biochemical parasitology, 1993, 62 1: Pages 9-17. DOI: 10.1016/0166-6851(93)90172-t