VH 032 amide-alkylC3-acid is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development. It incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. VH 032 amide-alkylC3-acid is part of a range of functionalized tool molecules for PROTAC R&D.
(S,R,S)-AHPC-C3-COOH (compound 28i) is a carboxylic acid derivative of the VHL E3 ubiquitin ligase ligand-Linker conjugate. (S,R,S)-AHPC-C3-COOH can be used to synthesize PROTACs[1].